#1 overall pick in the 2004 NFL draft out of the University of Mississippi, where he holds 45 single-game, season and career records.
He was drafted by the San Diego Chargers as the 1st draft pick overall in the 2004 NFL Draft. But refused to play in San Diego, and was traded to New York Giants for Philip Rivers. When New York Giants played against the San Diego Chargers in Manning's rookie year, New York lost.
On September 10, 2006 Eli and his older brother, Peyton Manning, made NFL history, because it was the first time in NFL history two brothers who play starting quarterback played against one another.
In 2008, he led The New York Giants to the Super Bowl XLII (42) victory over Tom Brady and the New England Patriots. He was named MVP. Also in 2012's Super Bowl XLVI (46).
Married college sweetheart Abby McGrew during a sunset ceremony at the One & Only Palmilla resort in Los Cabos, Mexico. (19 April 2008).