His favorite movie is Rear Window (1954) by Alfred Hitchcock.
Has performed magic tricks on "The Tonight Show Starring Johnny Carson" (1962), "Late Show with David Letterman" (1993), "The Tonight Show with Jay Leno" (1992), "Ellen: The Ellen DeGeneres Show" (2003) and "The Late Late Show with Craig Ferguson" (2005).
Was in a relationship with Robyn Lively (1992-1993), when they worked together on the set of "Doogie Howser, M.D." (1989).
Was in a relationship with Christine Taylor (1997-1998).
Typically, actors playing themselves on film are listed "as Himself" in the film's credits. Due to the over-the-top, outlandish nature of his role in Harold & Kumar Go to White Castle (2004) and Harold & Kumar Escape from Guantanamo Bay (2008), he requested that his credit read "Neil Patrick Harris" instead of "as Himself". This was to make clear that he was playing a fictional character that was in no way a true representation of himself.
Has been in a committed relationship with stage and screen actor David Burtka, his partner since 2004.
Is an avid Les Miserables fan, and performed the song "The Confrontation" with his co-star Jason Segel (both of "How I Met Your Mother" (2005) fame) live on "The Megan Mullally Show" (2006). He performed the role of Javert, to wild cheers from the audience.
Enjoys Red Bull so much on and off the set of "How I Met Your Mother" (2005) that he was given a lifetime supply of it and a mini-refrigerator by the company that makes the drink because of the amount of free advertising he has given it.
Friends with his "How I Met Your Mother" (2005) co-star, Alyson Hannigan.
He was the "Not My Job" guest on the April 5, 2008, episode of the National Public Radio quiz show "Wait Wait... Don't Tell Me!".
According to an oral history of "Dr. Horrible's Sing-Along Blog" (2008) published in July 2008 in Entertainment Weekly, he auditioned to play the doctor role on "Firefly" (2002) that was eventually filled by Sean Maher.
Recipient of the 2009 The Trevor Life Award, which annually honors an "individual who, through his or her example, support, volunteerism and/or occupation, is an inspiration to Lesbian, Gay, Bisexual, Transgender, or Questioning youth." The award is presented by The Trevor Project, a national crisis and suicide prevention organization helping LGBTQ young people who are facing familial rejection or considering suicide. The next year, he was elected to the Board of Directors of the Trevor Project.
In one year, he hosted The 7th Annual TV Land Awards (2009) (TV), The 63rd Annual Tony Awards (2009) (TV), and The 61st Primetime Emmy Awards (2009) (TV). All three ceremonies featured him singing a song about the occasion that had been written for him by Marc Shaiman and Scott Wittman.
All in the same award season, he hosted The 61st Primetime Emmy Awards (2009) (TV) and The 63rd Annual Tony Awards (2009) (TV), presented an award at The 67th Annual Golden Globe Awards (2010) (TV) and had an opening act at The 82nd Annual Academy Awards (2010) (TV).
In 2010, Time Magazine named Harris one of their 100 Most Influential People in the World. Joss Whedon wrote the short article on Harris in the issue.
Harris and his partner, David Burtka, have two children, Gideon Scott and Harper Grace, born on October 12, 2010.
On October 12, 2010, his and David Burtka's twins, son Gideon Scott and daughter Harper Grace, were born via surrogate.
In June 24, 2011, Harris and David Burtka announced their engagement via Twitter, stating that they had proposed to each other five years ago but kept the engagement secret until same-sex marriage became legal.
Received a star on the Hollywood Walk of Fame [September 2011].