She has played a hot, ditzy, sexy love interest for Kelsey Grammer's Frasier Crane character when he was trying to get over other women on "Cheers" (1982) and again on "Frasier" (1993) (though she was not playing the same character).
She has won a Theater World Award for Most Promising Newcomer for her work in Tina Howe's play, "One Shoe Off", at The Joseph Papp Theater. She also received a Dramalogue Award for her work in the play, "Vanities". She won a Gemini Award for Best Actress for her role in Showtime's made-for-TV film, Heads (1994) (TV), and a nomination for a Cable ACE Award for her work on "It's Garry Shandling's Show." (1986).
Wore the exact same wig in Bullets Over Broadway (1994) and Return to Babylon (2012).
Lenny von Dohlen, who co-starred with Jennifer in Bird of Prey (1995) and her sister Meg Tilly in Leaving Normal (1992), said, "They have a fountain of emotion that keeps coming, even after someone yells cut, but the fountain comes from different bodies of water," he adds. "Meg is an ocean, Jennifer is a rushing river."
She ranked #23 in Celebrity Sleuth 25 Sexiest Women of 1995
Followed up her World Series of Poker win with a victory in the "World Poker Tour" (2003) Ladies Night, to be broadcast during the fourth season of WPT.
In 2005, won the Ladies-Only No Limit Texas Hold 'Em event at the World Series of Poker, becoming the first celebrity to win an open (as opposed to celebrity-only) WSOP tournament and earn a World Series bracelet. She beat out exactly 600 other women to take the championship.