In 1991, she won the Ian Charleson Award for "Tartuffe".
In 1992, she won the Radio Times Awards for Best Newcomer for "The Camomile Lawn" (1992).
Had a relationship with Colin Firth whom she met while filming "Pride and Prejudice" (1995).
When casting for his film Sunshine (1999), director István Szabó didn't know she was Rosemary Harris' daughter in real life.
Her real life mother, actress Rosemary Harris, played the elder versions of her character Valerie in István Szabó's Sunshine (1999) and Calypso, in "The Camomile Lawn" (1992).
She was nominated for a Laurence Olivier Theatre Award in 2000 (1999 season) for Best Actress for her performance in "The Real Thing" at the Donmar Warehouse and at the Albery Theatre.
In 2000 she won the Variety Cub Showbusiness Awards for Best Stage Actress for The Real Thing.
Won Broadway's 2000 Tony Award as Best Actress (Play) for a revival of Tom Stoppard's "The Real Thing." One of her competitors who did not win was her mother, Rosemary Harris.
In 2000 she won the the Theatre World Award Best Actress in for The Real Thing.
Has won two Tony Awards: Best Actress in a Play in 2000 for "The Real Thing" and Best Featured Actress in a Play in 2007 for "The Coast of Utopia". Both of these plays were written by Tom Stoppard.
In 2000 she won a nomination at the Outer Critics Circle for Outstanding Featured Actress in a Play for The Real Thing.
2007: nominated Best Leading Actress in a Play at the Outer Critics Circle for The Coast of Utopia.
Won 2007 Tony Award Best Featured Actress in a Play for The Coast of Utopia.
She played "Brini Glass", George Clooney's lawyer-colleague-girlfriend in Michael Clayton (2007), but her scenes ended up on the cutting room floor. She can be seen in the background (unfocused) for a few seconds near the end of the film where Clayton's "death" is announced at the boardroom meeting. Clooney sent her a personal note apologizing for this exclusion from the film.
Auditioned for the title character in Rachel Getting Married (2008), but lost the part to Rosemarie DeWitt. Director Jonathan Demme referred to her for the female lead in "A Gifted Man" (2011).
Filmed scenes for the pilot of "Game of Thrones" (2011) as the character 'Catelyn Stark', however once the series was picked up she dropped out due to family commitments and was subsequently replaced by Michelle Fairley who re-filmed all her scenes.