Daughter of acting coach Burt Lane and Playboy centerfold Colleen Farrington (Miss October 1957).
August 1979: Was on the cover of Time Magazine at the age of 14.
When she was 13, George Roy Hill wanted her to star opposite Laurence Olivier in his film A Little Romance (1979). At the time, she was working on Broadway for Joseph Papp at the Public Theatre in the original production of "The Runaways". Both Hill and Papp wanted her, and a series of telegrams among Papp, Hill, Olivier' and her father transpired, with Hill, Olivier and Diane's father wanting her in the film, and Papp wanting to keep her in the play. She ended up doing the film.
1980: She was hit in the eye with a tennis ball, the impact of which caused permanent pupil dilation.
While filming The Outsiders (1983), co-star Tom Cruise received the script for Risky Business (1983) and asked her to co-star with him in the film as Lana. She stated that her father would "never" let her star as a prostitute and the role went to Rebecca De Mornay.
Turned down co-starring role in Risky Business (1983).
Has starred with Richard Gere in 3 movies to date: The Cotton Club (1984); Unfaithful (2002); and Nights in Rodanthe (2008).
In her off time, she likes to travel, ride her horses and go walking. She also enjoys keeping fit and does yoga. She especially loves to spend as much time as possible with her daughter, Eleanor Lambert, whose father is her ex-husband Christopher Lambert of Highlander (1986) fame.
Turned down the role of Kathryn Murphy in The Accused (1988). Kelly McGillis got the part.
Met first husband Christopher Lambert while filming Love Dream (1988) (aka "Priceless Beauty (1988)), together. They eventually had a daughter, Eleanor Lambert, and later divorced.
 Daughter Eleanor Lambert born. Father is ex-husband Christopher Lambert.
Collects antique furniture and has a strange fetish - she admitted in Playboy (1995) that she has "a thing for really high thigh-boots. I have a cool collection! I love high heels."
Auditioned for the role of Avery Bishop in Jerry Maguire (1996).
February 2000: Admitted in Esquire Magazine that she had had affairs with both Timothy Hutton and Christopher Atkins.
9/14/01: Two of her movies - Hard Ball (2001) and The Glass House (2001) - opened in theaters in the US on the same day. They were the top two movies at the box office that weekend.
Her father passed away shortly before Unfaithful (2002), in which she gave an Academy Award-nominated performance, was released. He did see a rough cut of the film three weeks before his death.
2003: Attended the Oscars with Josh Brolin.
July 2003: Engaged to actor Josh Brolin.
2003: Voted one of People Magazine's "Most Beautiful People in the World".
2004: Voted one of the "World's Most Desirable Women".
Was considered for the role of Ana in the 2004 remake of Dawn of the Dead (2004). The part eventually went to Sarah Polley.
Was #79 on VH1's "100 Greatest Kid Stars" (2005).